A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
Related Products
Research Tool(s)
15888Doxepin (hydrochloride)
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Doxepin (hydrochloride) (CRM)

A 1 mg/ml solution in methanol

Item No. 19039

Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-(dibenz[b,e]oxepin-11(6H)-ylidene)-N,N-dimethyl-1-propanamine, monohydrochloride
CAS Number
1229-29-4
Molecular Formula
C19H21NO • HCl
Formula Weight
315.8
Formulation
A 1 mg/ml solution in methanol
SMILES
CN(C)CC/C=C1C2=C(C=CC=C2)COC3=C/1C=CC=C3.Cl
InChi Code
InChI=1S/C19H21NO.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H/b17-11-;
InChi Key
MHNSPTUQQIYJOT-CULRIWENSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    1 mg

    $28

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    Product Description

    Doxepin (hydrochloride) (CRM) (Item No. 19039) is a certified reference material categorized as an antidepressant.1 Doxepin reduces immobility time in the forced swim test in a mouse model of chronic stress-induced depression.2 Formulations containing doxepin have been used in the treatment of depression and insomnia. This product is intended for analytical forensic applications. This product is also available as a general research tool (Item No. 15888).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tatsumi, M., Groshan, K., Blakely, R.D., et al. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur. J. Pharmacol. 340(2-3), 249-258 (1997).

    2. Kim, Y.R., Park, B.-K., Kim, Y.H., et al. Antidepressant effect of Fraxinus rhynchophylla Hance extract in a mouse model of chronic stress-induced depression. BioMed. Res. Int. 8249563 (2018).