A PPARγ agonist
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Edaglitazone

Item No. 19117

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-[[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzo[b]thien-7-yl]methyl]-2,4-thiazolidinedione
CAS Number
213411-83-7
Synonyms
  • BM 13.1258
Molecular Formula
C24H20N2O4S2
Formula Weight
464.6
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 30 mg/ml
λmax
218, 271 nm
SMILES
CC(OC(C1=CC=CC=C1)=N2)=C2CCOC3=C4C(SC=C4)=C(CC5SC(NC5=O)=O)C=C3
InChi Code
InChI=1S/C24H20N2O4S2/c1-14-18(25-23(30-14)15-5-3-2-4-6-15)9-11-29-19-8-7-16(21-17(19)10-12-31-21)13-20-22(27)26-24(28)32-20/h2-8,10,12,20H,9,11,13H2,1H3,(H,26,27,28)
InChi Key
HAAXAFNSRADSMK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $119

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    10 mg

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    25 mg

    $467

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    Cayman Chemical
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    OBESITY RESEARCH SOLUTIONS
    Product Description

    Edaglitazone is an agonist of peroxisome proliferator-activated receptor γ (PPARγ).1 It activates PPARγ in a reporter assay using CV-1 cells expressing murine PPARγ2 when used at concentrations ranging from 0.1 to 1 μM. Edaglitazone (1, 5, and 25 μM) increases [3H]2-deoxyglucose transport in the presence and absence of insulin and increases glycogen synthesis in the presence of insulin in soleus muscle strips isolated from obese rats.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fürnsinn, C., Brunmair, B., Meyer, M., et al. Chronic and acute effects of thiazolidinediones BM13.1258 and BM15.2054 on rat skeletal muscle glucose metabolism. Br. J. Pharmacol. 128(6), 1141-1148 (1999).