An enzyme substrate for glycolysis and gluconeogenesis pathways
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Phosphoenolpyruvic Acid (potassium salt)

Item No. 19192

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(phosphonooxy)-2-propenoic acid, monopotassium salt
CAS Number
4265-07-0
Synonyms
  • PEP-K
Molecular Formula
C3H4O6P • K
Formula Weight
206.1
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
C=C(C(O)=O)OP([O-])(O)=O.[K+]
InChi Code
InChI=1S/C3H5O6P.K/c1-2(3(4)5)9-10(6,7)8;/h1H2,(H,4,5)(H2,6,7,8);/q;+1/p-1
InChi Key
SOSDSEAIODNVPX-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

    $40

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    500 mg

    $63

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    1 g

    $102

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    5 g

    $193

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    Cayman Chemical
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    Product Description

    Phosphoenolpyruvic acid plays a role in both glycolysis and gluconeogenesis. During glycolysis, it is formed by the action of enolase on 2-phosphoglycerate and is metabolized to pyruvate by pyruvate kinase.1 One molecule of ATP is formed during its metabolism in this pathway. During gluconeogenesis, it is formed from phosphoenolpyruvate carboxykinase-catalyzed oxaloacetate decarboxylation and GTP hydrolysis.1,2,3 In plants, it is metabolized to form aromatic amino acids and also serves as a substrate for phosphoenolpyruvate carboxylase-catalyzed carbon fixation.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Muñoz, M.E., and Ponce, E. Pyruvate kinase: Current status of regulatory and functional properties. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 135(2), 197-218 (2003).

    2. Matte, A., Tari, L.W., Goldie, H., et al. Structure and mechanism of phosphoenolpyruvate carboxykinase. The Journal of Biological Chemisty 272(13), 8105-8108 (1997).

    3. Hanson, R.W., and Garber, A.J. Phosphoenolpyruvate carboxykinase. I. Its role in gluconeogenesis. Am. J. Clin. Nutr. 25(10), 1010-1021 (1972).

    4. Herrmann, K.M. The shikimate pathway: Early steps in the biosynthesis of aromatic compounds. Plant Cell 7(7), 907-919 (1995).