An antioxidant bile pigment
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Alternative(s)
36337Biliverdin (technical grade)
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Product Categories

Product Type

Biochemicals
Antioxidants

Research Area

Endocrinology & Metabolism
Biliary System

Biliverdin (hydrochloride)

Item No. 19257

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,18-diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid, monohydrochloride
CAS Number
856699-18-8
Molecular Formula
C33H34N4O6 • HCl
Formula Weight
619.1
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMF:PBS(pH 7.2)(1:1): 0.5 mg/mlDMSO: 20 mg/ml
λmax
310, 376, 689 nm
SMILES
OC(CCC1=C(/C=C2C(CCC(O)=O)=C(C)C(/C=C3NC(C(C=C)=C\3C)=O)=N/2)NC(/C=C4NC(C(C)=C\4C=C)=O)=C1C)=O.Cl
InChi Code
InChI=1S/C33H34N4O6.ClH/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26;/h7-8,13-15,35H,1-2,9-12H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41);1H/b26-13-,27-14-,28-15
InChi Key
KTRFJVRKVQROKS-UJCZHUFNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    10 mg

    $37

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    50 mg

    $136

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    100 mg

    $235

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    Product Description

    Biliverdin is a green bile pigment produced from the oxidation of heme in a reaction catalyzed by heme oxygenase and is further reduced to bilirubin (Item No. 17161) by biliverdin reductase.1,2 Biliverdin regulates the cellular heme degradation process by inhibiting substrates from binding to the catalytic site of heme oxygenase. Bile pigments such as biliverdin are known to possess anti-mutagenic and antioxidant properties.3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu, Y., Moënne-Loccoz, P., Loehr, T.M., et al. Heme oxygenase-1, intermediates in verdoheme formation and the requirement for reduction equivalents. The Journal of Biological Chemisty 272, 6909-6917 (1997).

    2. Maines, M.D. The heme oxygenase system: A regulator of second messenger gases. Annu. Rev. Pharmacol. Toxicol. 37, 517-554 (1997).

    3. Bulmer, A.C., Ried, K., Blanchfield, J.T., et al. The anti-mutagenic properties of bile pigments. Mutat. Res. 658(1-2), 28-41 (2008).

    4. Mölzer, C., Huber, H., Steyrer, A., et al. In vitro antioxidant capacity and antigenotoxic properties of protoporphyrin and structurally related tetrapyrroles. Free Radic. Res. 46(11), 1369-1377 (2012).