A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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Reference Material(s)
18325Naltrexone-d3
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Naltrexone-d3 (CRM)

A 100 μg/ml solution in methanol

Item No. 19323

Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
17-((cyclopropyl-d1)methyl-d2)-4,5α-epoxy-3,14-dihydroxy-morphinan-6-one
CAS Number
1261080-26-5
Molecular Formula
C20H20D3NO4
Formula Weight
344.4
Formulation
A 100 μg/ml solution in methanol
SMILES
O[C@]12[C@]3(CCN(C([2H])([2H])C4([2H])CC4)[C@@H]2C5)[C@](OC6=C3C5=CC=C6O)([H])C(CC1)=O
InChi Code
InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1/i10D2,11D
InChi Key
DQCKKXVULJGBQN-VOVHGNGRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 µg

    $303

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    Product Description

    Naltrexone-d3 (Item No. 19323) is a certified reference material intended for use as an internal standard for the quantification of naltrexone (Item Nos. 15520 | ISO60192) by GC- or LC-MS. Naltrexone is categorized as an opioid antagonist.1 Formulations containing naltrexone have been used in the treatment of alcohol dependence and in the prevention of relapse to opioid dependence. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ghirmai, S., Azar, M.R., Polgar, W.E., et al. Synthesis and biological evaluation of α- and β-6-amido derivatives of 17-cyclopropylmethyl-3, 14β-dihydroxy-4, 5α-epoxymorphinan: Potential alcohol-cessation agents. J. Med. Chem. 51(6), 1913-1924 (2008).