Pricing updated 2019-07-17. Prices are subject to change without notice.
Amorfrutin B is a partial agonist of the peroxisome proliferator-activated receptor γ (PPARγ; Ki = 19 nM and EC50 = 73 nM) that was first isolated from A. fruticosa.1 It binds to PPARα and PPARβ/δ with Ki values of 2.6 and 1.7 µM, respectively.1 In insulin-resistant mice, 100 mg/kg/day amorfrutin B is reported to improve insulin sensitivity, glucose tolerance, and plasma lipid concentrations after two weeks of treatment.1
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Weidner, C., Wowro, S.J., Freiwald, A., et al. Amorfrutin B is an efficient natural peroxisome proliferator-