A phenol with diverse biological activities
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Ferulic Acid

Item No. 19871

Technical Information
Formal Name
3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid
CAS Number
1135-24-6
Synonyms
  • Coniferic Acid
  • 4-hydroxy-3-Methoxycinnamic Acid
  • NSC 2821
  • NSC 51986
  • NSC 674320
Molecular Formula
C10H10O4
Formula Weight
Purity
≥98%
A crystalline solid
DMF: 20 mg/mlDMF:PBS(pH 7.2)(1:6): 0.14 mg/mlDMSO: 15 mg/mlEthanol: 10 mg/ml
λmax
218, 234, 323 nm
SMILES
COC1=C(O)C=CC(/C=C/C(O)=O)=C1
InChi Code
InChI=1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+
InChi Key
KSEBMYQBYZTDHS-HWKANZROSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Ferulic acid is a phenol that has been found in apples and has diverse biological activities.1,2,3,4 It is active against the yeast S. cerevisiae when used at a concentration of 250 ppm and the bacteria E. coli, S. aureus, and B. cereus when used at a concentration of 500 µg/ml.1,2 Dietary administration of ferulic acid (0.2% w/w) reduces serum total cholesterol levels in a rat model of diet-induced hypercholesterolemia.3 It suppresses benzo(a)pyrene-induced forestomach tumor formation in mice.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Baranowski, J.D., Davidson, P.M., Nagel, C.W., et alInhibition of Saccharomyces cerevisiae by naturally occurring hydroxycinnamates. J. Food Sci. 45(3), 592-594 (1980).

    2. Herald, P.J., and Davidson, P.M. Antibacterial activity of selected hydroxycinnamic acids. J. Food Sci. 48(4), 1378-1379 (1983).

    3. Sharma, R.D. Effect of hydroxy acids on hypercholesterolaemia in rats. Atherosclerosis 37(3), 463-468 (1980).

    4. Wattenburg, L.W., Coccia, J.B., and Lam, L.K. Inhibitory effects of phenolic compounds on benzo(a)pyrene-induced neoplasia. Cancer Res. 40(8 Pt 1), 2820-2823 (1980).