An intermediate in aromatic amino acid metabolism
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Isomer(s)
39643Vanillic Acid
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Homogentisic Acid

Item No. 20045

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,5-dihydroxy-benzeneacetic acid
CAS Number
451-13-8
Synonyms
  • Alcapton
  • NSC 88940
  • 2,5-dihydroxy-α-Toluic Acid
Molecular Formula
C8H8O4
Formula Weight
168.1
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mLDMSO: 16 mg/mLEthanol: 16 mg/mLPBS (pH 7.2): 5 mg/mL
λmax
296 nm
SMILES
OC1=C(CC(O)=O)C=C(O)C=C1
InChi Code
InChI=1S/C8H8O4/c9-6-1-2-7(10)5(3-6)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)
InChi Key
IGMNYECMUMZDDF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    50 mg

    $68

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    100 mg

    $106

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    250 mg

    $216

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    500 mg

    $332

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    Product Description

    Homogentisic acid is a phenolic acid and intermediate in the catabolism of aromatic amino acids, including phenylalanine and tyrosine. It is formed in excess during alkaptonuria, whereas excess deposition of homogentisic acid in connective tissues produces ochronosis.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Mistry, J.B., Bukhari, M., and Taylor, A.M. Alkaptonuria. Rare Dis. 1:e27475, (2013).