An antifungal agent
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Econazole (nitrate)

Item No. 20223

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, mononitrate
CAS Number
24169-02-6
Synonyms
  • NSC 243115
  • SQ 13,020
Molecular Formula
C18H15Cl3N2O • HNO3
Formula Weight
444.7
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 25 mg/mlDMSO:PBS(pH 7.2) (1:2): 0.3 mg/mlEthanol: 0.1 mg/ml
SMILES
ClC1=CC(Cl)=CC=C1C(CN2C=NC=C2)OCC3=CC=C(Cl)C=C3.O=[N](O)=O
InChi Code
InChI=1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)
InChi Key
DDXORDQKGIZAME-UHFFFAOYSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

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    Cayman Chemical
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    Product Description

    Econazole (nitrate) is an azole-based antifungal compound that acts by inhibiting the 14α-demethylation of lanosterol (Item No. 19521), which consequently leads to the inhibition of ergosterol (Item No. 19850) synthesis in fungal cell membranes.1 It demonstrates broad-spectrum activity against dermatophytes, Candida species, other pathogenic yeasts, and some Gram-positive bacteria.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fromtling, R.A. Overview of medically important antifungal azole derivatives. Clin. Microbiol. Rev. 1(2), 187-217 (1988).