A fluoroquinolone antibiotic
Related Products
Labeled Version(s)
33809Enrofloxacin-d5
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Enrofloxacin

Item No. 20301

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
CAS Number
93106-60-6
Synonyms
  • BAY-Vp 2674
  • ENR
  • PD 160788
Molecular Formula
C19H22FN3O3
Formula Weight
359.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMF:PBS (pH 7.2) (1:1): 0.5 mg/mlDMSO: 1 mg/ml with warming
λmax
280, 318 nm
SMILES
CCN1CCN(C2=C(F)C=C(C(C(C(O)=O)=CN3C4CC4)=O)C3=C2)CC1
InChi Code
InChI=1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26)
InChi Key
SPFYMRJSYKOXGV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 g

    $36

    Add

    5 g

    $86

    Add

    10 g

    $132

    Add

    25 g

    $195

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    Enrofloxacin is a fluoroquinolone antibiotic.1 It is active against panels of Campylobacter, E. coli, and Salmonella isolates (mean MIC50s = 0.06, 0.5, and 0.03 µg/ml, respectively). It is also active against equine isolates of L. intracellularis (MICs = 0.125-0.5 µg/ml).2 Enrofloxacin inhibits bacterial DNA gyrase.3 In vivo, enrofloxacin (10 mg/kg) increases survival in a mouse model of enteropathogenic E. coli-induced sepsis. Formulations containing enrofloxacin have been used in the treatment of veterinary bacterial infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Randall, L., Ridley, A., Lemma, F., et al. In vitro investigations into the use of antimicrobials in combination to maintain efficacy of fluoroquinolones in poultry. Res. Vet. Sci. 108, 47-53 (2016).

    2. Pereira, C.E.R., Resende, T.P., Vasquez, E., et al. In vitro antimicrobial activity against equine Lawsonia intracellularis strains. Equine Vet. J. 51(5), 665-668 (2019).

    3. Slate, A.R., Bandyopadhyay, S., Francis, K.P., et al. Efficacy of enrofloxacin in a mouse model of sepsis. J. Am. Assoc. Lab. Anim. Sci. 53(4), 381-386 (2014).