A rifamycin antibiotic
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Labeled Version(s)
28708Rifapentine-d9
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Rifapentine

Item No. 20307

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-[[(4-cyclopentyl-1-piperazinyl)imino]methyl]-rifamycin
CAS Number
61379-65-5
Synonyms
  • Cyclopentylrifampicin
  • DL-473
  • MDL 473
Molecular Formula
C47H64N4O12
Formula Weight
877.0
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:6): 0.14 mg/mlEthanol: 2 mg/ml
λmax
237, 253, 336, 478 nm
SMILES
OC1=C2C(C(O)=C(C)C(O[C@]3(C)O/C=C/[C@H](OC)[C@@H](C)[C@]([C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)\C(N4)=O)(OC(C)=O)[H])=C2C3=O)=C(O)C4=C1/C=N/N5CCN(C6CCCC6)CC5
InChi Code
InChI=1S/C47H64N4O12/c1-24-13-12-14-25(2)46(59)49-37-32(23-48-51-20-18-50(19-21-51)31-15-10-11-16-31)41(56)34-35(42(37)57)40(55)29(6)44-36(34)45(58)47(8,63-44)61-22-17-33(60-9)26(3)43(62-30(7)52)28(5)39(54)27(4)38(24)53/h12-14,17,22-24,26-28,31,33,38
InChi Key
WDZCUPBHRAEYDL-GZAUEHORSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

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    Cayman Chemical
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    Product Description

    Rifapentine is a long-lasting rifamycin antibiotic that inhibits DNA-dependent RNA polymerases and is effective against Mycobacterium species, including M. tuberculosis, as well as experimental infections caused by S. aureus, S. pyogenes group A, S. pneumoniae, and K. pneumoniae.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Arioli, V., Berti, M., Carniti, G., et al. Antibacterial activity of DL 473, a new semisynthetic rifamycin derivative. J. Antibiot. (Tokyo) 34(8), 1026-1032 (1981).

    2. Sharma, S.K., Sharma, A., Kadhiravan, T., et al. Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB. Cochrane Database Syst. Rev. 7, CD007545 (2013).