An internal standard for the quantification of rifapentine
Related Products
Unlabeled Version(s)
20307Rifapentine
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Rifapentine-d9

Item No. 28708

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-[[(4-cyclopentyl-1-piperazinyl)imino]methyl]-rifamycin-d9
Synonyms
  • Cyclopentylrifampicin-d9
Molecular Formula
C47H55D9N4O12
Formula Weight
886.1
Purity
≥99% deuterated forms (d1-d9)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: solubleDMSO: solubleMethanol: soluble
SMILES
OC1=C2C(C(O)=C(C)C(O[C@]3(C)O/C=C/[C@H](OC)[C@@H](C)[C@]([C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)\C(N4)=O)(OC(C)=O)[H])=C2C3=O)=C(O)C4=C1/C=N/N5CCN(C6([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C6([2H])[2H])CC5
InChi Code
InChI=1S/C47H64N4O12/c1-24-13-12-14-25(2)46(59)49-37-32(23-48-51-20-18-50(19-21-51)31-15-10-11-16-31)41(56)34-35(42(37)57)40(55)29(6)44-36(34)45(58)47(8,63-44)61-22-17-33(60-9)26(3)43(62-30(7)52)28(5)39(54)27(4)38(24)53/h12-14,17,22-24,26-28,31,33,38-39,43,53-57H,10-11,15-16,18-21H2,1-9H3,(H,49,59)/b13-12+,22-17+,25-14-,48-23+/t24-,26+,27+,28+,33-,38-,39+,43+,47-/m0/s1/i10D2,11D2,15D2,16D2,31D
InChi Key
WDZCUPBHRAEYDL-ZZSWSMFNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

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    Product Description

    Rifapentine-d9 is intended for use as an internal standard for the quantification of rifapentine (Item No. 20307) by GC- or LC-MS. Rifapentine is a long-lasting rifamycin antibiotic that inhibits DNA-dependent RNA polymerases and is effective against Mycobacterium species, including M. tuberculosis, as well as experimental infections caused by S. aureus, S. pyogenes group A, S. pneumoniae, and K. pneumoniae.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Arioli, V., Berti, M., Carniti, G., et al. Antibacterial activity of DL 473, a new semisynthetic rifamycin derivative. J. Antibiot. (Tokyo) 34(8), 1026-1032 (1981).

    2. Sharma, S.K., Sharma, A., Kadhiravan, T., et al. Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB. Cochrane Database Syst. Rev. 7, CD007545 (2013).