A sulfonamide antibiotic
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Sulfacetamide (sodium salt)

Item No. 20377

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(4-aminophenyl)sulfonyl]-acetamide, monosodium salt
CAS Number
127-56-0
Synonyms
  • N-acetyl Sulfanilamide
Molecular Formula
C8H9N2O3S • Na
Formula Weight
236.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 15 mg/mEthanol: 1 mg/mlPBS (pH 7.2): 5 mg/ml
λmax
267 nm
SMILES
NC1=CC=C(S([N-]C(C)=O)(=O)=O)C=C1.[Na+]
InChi Code
InChI=1S/C8H10N2O3S.Na/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8;/h2-5H,9H2,1H3,(H,10,11);/q;+1/p-1
InChi Key
PQMSFAORUFMASU-UHFFFAOYSA-M
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    50 g

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    Cayman Chemical
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    Product Description

    Sulfacetamide is a sulfonamide antibiotic that is bacteriostatic against Gram-positive and Gram-negative bacteria. It inhibits dihydropteroate synthase (IC50 = 9.6 µM), blocking the synthesis of dihydrofolic acid, and also inhibits bacterial 4-aminobenzoic acid (Item No. 18659), which is required for the synthesis of folic acid.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Prabhu, V., Lui, H., and King, J. Arabidopsis dihydropteroate synthase: general properties and inhibition by reaction product and sulfonamides. Phytochemistry 45(1), 23-27 (1997).