A trichothecene mycotoxin and an active metabolite of T-2 toxin
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Parent Compound(s)
11444T-2 Toxin
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T-2 Tetraol

Item No. 20432

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
12,13-epoxy-trichothec-9-ene-3α,4β,8α,15-tetrol
CAS Number
34114-99-3
Synonyms
  • T-2 Toxin Tetraol
Molecular Formula
C15H22O6
Formula Weight
298.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Dichloromethane: 10 mg/ml
SMILES
CC1=C[C@]2([H])[C@]([C@]([C@H](O)[C@H]3O)(C)[C@@]4(OC4)[C@]3([H])O2)(CO)C[C@@H]1O
InChi Code
InChI=1S/C15H22O6/c1-7-3-9-14(5-16,4-8(7)17)13(2)11(19)10(18)12(21-9)15(13)6-20-15/h3,8-12,16-19H,4-6H2,1-2H3/t8-,9+,10+,11+,12+,13+,14+,15-/m0/s1
InChi Key
ZAXZBJSXSOISTF-LYFQSNBGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $526

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    Product Description

    T-2 tetraol is a trichothecene mycotoxin that has been found in F. tricinctum and an active metabolite of T-2 toxin (Item No. 11444).1 It induces cell death (LC50 = 9 µg/ml), reduces proliferation (EC50 = 0.25 µg/ml), and decreases protein and DNA synthesis in primary human fibroblasts when used at a concentration of 10 µg/ml. T-2 tetraol is toxic to newly hatched chicks (LD50 = 33.79 mg/kg).2 It reduces feed consumption and weight gain in newly hatched chicks when administered at a dose of 40 mg/kg. T-2 tetraol has been found in Fusarium-contaminated barley kernels.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Oldham, J.W., Allred, L.E., Milo, G.E., et al. The toxicological evaluation of the mycotoxins T-2 and T-2 tetraol using normal human fibroblasts in vitro. Toxicol. Appl. Pharmacol. 52(1), 159-168 (1979).

    2. Chi, M.S., Robison, T.S., Mirocha, C.J., et al. Acute toxicity of 12,13-epoxytrichothecenes in one-day-old broiler chicks. Appl. Environ. Microbiol. 35(4), 636-640 (1978).

    3. Perkowski, J., Kiecana, I., and Kaczmarek, Z. Natural occurrence and distribution of Fusarium toxins in contaminated barley cultivars. Eur. J. Plant Pathol. 109, 331-339 (2003).