An essential B vitamin
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Active Metabolite(s)
32750Dihydrofolic Acid
Labeled Version(s)
28485Folic Acid-d4
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Folic Acid

Item No. 20515

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
CAS Number
59-30-3
Synonyms
  • NSC 3073
  • Vitamin B9
Molecular Formula
C19H19N7O6
Formula Weight
441.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 20 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
λmax
283 nm
SMILES
O=C1C2=NC(CNC3=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C3)=CNC2=NC(N)=N1
InChi Code
InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
InChi Key
OVBPIULPVIDEAO-LBPRGKRZSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    10 g

    $36

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    25 g

    $59

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    50 g

    $103

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    100 g

    $169

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    Product Description

    Folic acid is an essential B vitamin.1 It is converted to folate in vivo, which is a necessary cofactor for a variety of biological processes, including nucleotide synthesis and, thus, DNA synthesis and repair, among others. A deficiency in dietary folic acid can lead to a range of developmental and cognitive disorders, most prominently neural tube defects and congenital heart defects.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Czeizel, A.E., Dudás, I., Vereczkey, A., et al. Folate deficiency and folic acid supplementation: The prevention of neural-tube defects and congenital heart defects. Nutrients 5(11), 4760-4775 (2013).

    2. Nair, M.K., Augustine, L.F., and Konapur, A. Food-based interventions to modify diet quality and diversity to address multiple micronutrient deficiency. Front. Public Health 3, 277 (2016).

    3. Sarmah, S., Muralidharan, P., and Marrs, J.A. Common congenital anomalies: Environmental causes and prevention with folic acid containing multivitamins. Birth Defects Res. C Embryo Today 108(3), 274-286 (2016).