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Trehalose is a natural non-reducing disaccharide composed of two α-glucose units. It is found in all major groups of organisms except vertebrates, has biological functions as an osmolyte, storage reserve, and stress protectant, and has diverse commercial applications.1,2,3 Trehalose can also induce or enhance autophagy.4
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1. A tale of two sugars: Trehalose 6-
2. Inhibition of trehalase activity enhances trehalose accumulation in transgenic plants. Plant Physiol. 113(1), 181-190 (1997).
3. Trehalose analogues: Latest insights in properties and biocatalytic production. Int. J. Mol. Sci. 16(6), 13729-13745 (2015).
4. Autophagy and apoptosis dysfunction in neurogegenerative disorders. Prog. Neurobiol. 112, 24-49 (2014).