A carbohydrate allergen
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Galactose-α-1,3-galactose

Item No. 45639

Technical Information
Formal Name
3-O-α-D-galactopyranosyl-D-galactose
CAS Number
13168-24-6
Synonyms
  • α-Gal
  • 3α-Galactobiose
Molecular Formula
C12H22O11
Formula Weight
Purity
≥95%
A solid
DMSO: Soluble: ≥10 m/mlPBS (7.2 pH): Slightly soluble: 0.1-1 mg/ml
SMILES
O[C@H]([C@H]([C@H]([C@@H](CO)O)O)O[C@@H]1[C@@H]([C@H]([C@H]([C@@H](CO)O1)O)O)O)C=O
InChi Code
InChI=1S/C12H22O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h2,4-13,15-21H,1,3H2/t4-,5+,6-,7+,8+,9+,10-,11-,12-/m1/s1
InChi Key
YGEHCIVVZVBCLE-FSYGUOKUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Galactose-α-1,3-galactose (α-Gal) is a carbohydrate allergen found in non-catarrhine mammals.1,2 It causes alpha-Gal syndrome (AGS), which is mediated by anti-α-Gal IgE antibodies primarily arising from tick bites, which results in red meat allergies. AGS can also originate from cetuximab exposure or xenotransplantation.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wilson, J.M., Schuyler, A.J., Schroeder, N., et alGalactose-α-1,3-galactose: Atypical food allergen or model IgE hypersensitivity? Curr. Allergy Asthma Rep. 17(1), 8 (2017).

    2. Cabezas-Cruz, A., Hodžić, A., Román-Carrasco, P., et alEnvironmental and molecular drivers of the α-Gal syndrome. Front. Immunol. 10, 1210 (2019).