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trans-4-phenyl-4-Piperidinocyclohexanol

Item No. 20565

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • PCHP
  • 1-(1-Phenyl-4-hydroxycyclohexyl)piperidine
  • 4-PPC
Technical Information
Formal Name
trans-4-phenyl-4-(1-piperidinyl)-cyclohexanol
CAS Number
78165-07-8
Molecular Formula
C17H25NO
Formula Weight
259.4
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 5 mg/mlEthanol: 10 mg/mlEthanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
SMILES
O[C@@H]1CC[C@@](C2=CC=CC=C2)(N3CCCCC3)CC1
InChi Code
InChI=1S/C17H25NO/c19-16-9-11-17(12-10-16,15-7-3-1-4-8-15)18-13-5-2-6-14-18/h1,3-4,7-8,16,19H,2,5-6,9-14H2/t16-,17-
InChi Key
KPRUAZBLIREHPD-QAQDUYKDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $176

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    Product Description

    trans-4-phenyl-4-Piperidinocyclohexanol (Item No. 20565) is an analytical reference standard that is structurally categorized as an arylcyclohexylamine. It is a metabolite of phencyclidine (PCP; Item No. ISO60194).1 trans-4-phenyl-4-Piperidinocyclohexanol inhibits dopamine uptake in rat striatal synaptosomes to a similar extent as PCP.2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sakamoto, T., Tanaka, A., and Nakahara, Y. Hair analysis for drugs of abuse XII. Determination of PCP and its major metabolites, PCHP and PPC, in rat hair after administration of PCP. J. Anal. Toxicol. 20(2), 124-130 (1996).

    2. Baba, A., Yamamoto, T., Yamamoto, H., et al. Effects of the major metabolite of phencyclidine, the trans isomer of 4-phenyl-4-(1-piperidinyl)cyclohexanol, on [3H]N-(1-[2-thienyl] cyclohexyl)-3,4-piperidine ([3H]TCP) binding and [3H]dopamine uptake in the rat brain. Neurosci. Lett. 182(1), 119-121 (1994).