A cyclic peptide hormone
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Somatostatin-14 (human, mouse, rat, porcine, bovine, ovine) (acetate)

Item No. 20809

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
somatostatin, monoacetate
CAS Number
54472-66-1
Molecular Formula
C76H104N18O19S2 • C2H4O2
Formula Weight
1697.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: 0.3 mg/ml
SMILES
[H]N[C@H](C(NCC(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N[C@]([C@@H](C)O)([H])C(N[C@H](C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CO)C1=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)CC3=CNC4=C3C=CC=C4)=O)CC5=CC=CC=C5)=O)CC6=CC=CC=C6)=O)=O)=O)CSSC[C@H](N1)C(O)=O)=O)=O)C.CC(O)=O
InChi Code
InChI=1S/C76H104N18O19S2.C2H4O2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77;1-2(3)4/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113);1H3,(H,3,4)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-;/m0./s1
InChi Key
GFYNCDIZASLOMM-HMAILDBGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $80

    Add

    5 mg

    $377

    Add

    10 mg

    $713

    Add

    25 mg

    $990

    Add
    Cayman Chemical
    Explore Obesity & Metabolic Disease Resources

    Discover high-quality research tools to investigate GLP-1 mechanisms and next-generation metabolic targets.

    OBESITY RESEARCH SOLUTIONS
    Product Description

    Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin.1 It is a somatostatin (SST) receptor agonist that binds to SST1, SST2, SST3, SST4, and SST5 (IC50s = 0.22, 0.10, 0.28, 1.23, and 0.30 nM, respectively, in CCL39 cells expressing human recombinant receptors).2 It inhibits cAMP accumulation induced by forskolin (Item No. 11018) in CCL39 cells expressing human recombinant SST1, SST2, SST3, SST4, and SST5 (EC50s = 6.16, 4.37, 17.38, 2.95, and 4.67 nM, respectively).3 Somatostatin-14 inhibits the release of growth hormone, prolactin, thyrotropin, glucagon, and insulin, as well as other signaling molecules.1,4,5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hadjidakis, D.J., Raptis, S.A., Souvatzoglou, A., et al. Differences between somatostatin-28 and somatostatin-14 with respect to their biological effects in healthy humans and acromegalics. Clin. Physiol. Biochem. 4(6), 372-383 (1986).

    2. Siehler, S., Seuwen, K., and Hoyer, D. Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies. Naunyn Schmiedebergs Arch. Pharmacol. 360(5), 488-499 (1999).

    3. Siehler, S., and Hoyer, D. Characterisation of human recombinant somatostatin receptors. 3. Modulation of adenylate cyclase activity. Naunyn Schmiedebergs Arch. Pharmacol. 360(5), 510-521 (1999).

    4. Gillies, G. Somatostatin: The neuroendocrine story. Trends Pharmacol. Sci. 18(3), 87-95 (1997).

    5. Joseph, I.M.P., Zavros, Y., Merchant, J.L., et al. A model for integrative study of human gastric acid secretion. J. Appl. Physiol. (1985) 94(4), 1602-1618 (2003).