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L-Theanine is the major amino acid found in Camellia sinensis, the source of green tea.1 It is an analog of the excitatory neurotransmitter, glutamate, and thusly, binds to glutamate receptors.2 L-Theanine can antagonize various glutamate receptor subtypes as well as inhibit glutamine and glutamate transporters, which has been shown to be neuroprotective in animal models of focal cerebral ischemia.2,3 Further, L-theanine is reported to increase brain levels of dopamine, serotonin, GABA, nerve growth factor, and brain-derived neurotrophic factor.2,3
WARNING This product is not for human or veterinary use.
1. Determination of theanine in commercial tea by liquid chromatography with fluorescence and diode array ultraviolet detection. J. Agric. Food Chem. 54(19), 7014-7019 (2006).
2. Pharmacology and therapeutic uses of theanine. Am. J. Health Syst. Pharm. 63(1), 26, 28-30 (2006).
3. The neuropharmacology of L-