An organosulfur compound
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Diallyl Sulfide

Item No. 20894

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,3'-thiobis-1-propene
CAS Number
592-88-1
Synonyms
  • Allyl Sulfide
  • DAS
  • NSC 20947
Molecular Formula
C6H10S
Formula Weight
114.2
Purity
≥95%
Formulation (Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMF:PBS (pH 7.2) (1:4): 0.2 mg/mlDMSO: 5 mg/mlEthanol: 3 mg/ml
λmax
220 nm
SMILES
C=CCSCC=C
InChi Code
InChI=1S/C6H10S/c1-3-5-7-6-4-2/h3-4H,1-2,5-6H2
InChi Key
UBJVUCKUDDKUJF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    25 g

    $37

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    50 g

    $66

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    100 g

    $99

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    Product Description

    Diallyl sulfide is a thioether found in garlic that can modulate the cytochrome P450 drug metabolizing system, activate the constitutive androstane receptor to regulate multidrug resistance-associated proteins, and upregulate the expression of detoxifying enzymes.1,2 Garlic-derived organosulfides such as diallyl sulfide have been shown to be highly protective from chemically-induced carcinogenesis in animals.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Maher, J.M., Cheng, X., Slitt, A.L., et al. Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver. Drug Metab. Dispos. 33(7), 956-962 (2005).

    2. Magesh, S., Chen, Y., and Hu, L. Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents. Med. Res. Rev. 32(4), 687-726 (2012).

    3. Xiao, D., Choi, S., Johnson, D.E., et al. Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2. Oncogene 23(33), 5594-5606 (2004).