A natural pentacyclic triterpenoid
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Isomer(s)
40136Taraxerol 29831α-Amyrin
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β-Amyrin

Item No. 20949

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β)-olean-12-en-3-ol
CAS Number
559-70-6
Synonyms
  • (+)-β-Amyrin
  • NSC 527971
  • Olean-12-en-3β-ol
Molecular Formula
C30H50O
Formula Weight
426.7
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 2 mg/ mlDMF:PBS (pH 7.2) (1:8): 0.1 mg/mlEthanol: 1 mg/ml
SMILES
CC1(C)[C@]2([H])CC[C@@]3(C)[C@]4(C)CC[C@@]5(C)CCC(C)(C)C[C@@]5([H])C4=CC[C@]3([H])[C@@]2(C)CC[C@@H]1O
InChi Code
InChI=1S/C30H50O/c1-25(2)15-16-27(5)17-18-29(7)20(21(27)19-25)9-10-23-28(6)13-12-24(31)26(3,4)22(28)11-14-30(23,29)8/h9,21-24,31H,10-19H2,1-8H3/t21-,22-,23+,24-,27+,28-,29+,30+/m0/s1
InChi Key
JFSHUTJDVKUMTJ-QHPUVITPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    1 mg

    $96

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    5 mg

    $393

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    10 mg

    $655

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    Product Description

    β-Amyrin is a natural pentacyclic triterpenoid commonly found in plants. It is a member of the oleanane group of secondary metabolites biosynthesized from squalene in the triterpenoid pathway. β-Amyrin inhibits collagen-induced platelet aggregation (IC50 = 10.5 µM), inhibits acetylcholinesterase (IC50 = 165 µM), and has antifungal and hepatoprotective effects.1,2,3,4 Extracts of certain plants, used in herbal medicine to treat inflammation, have been shown to contain β-amyrin, suggesting that this compound contributes to anti-inflammatory actions.5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ching, J., Chua, T.K., Chin, L.C., et al. Beta-amyrin from Ardisia elliptica Thunb. is more potent than aspirin in inhibiting collagen-induced platelet aggregation. Indian J. Exp. Biol. 48(3), 275-279 (2010).

    2. Jabeen, K., Javid, A., Ahmad, E., et al. Antifungal compounds from Melia azedarach leaves for management of Ascochyta rabiei, the cause of chickpea blight. Nat. Prod. Res. 25(3), 264-276 (2011).

    3. Oliveira, F.A., Chaves, M.H., Almeida, F.R., et al. Protective effect of alpha- and beta-amyrin, a triterpene mixture from Protium heptaphyllum (Aubl.) March. trunk wood resin, against acetaminophen-induced liver injury in mice. J. Ethnopharmacol. 98(1-2), 103-108 (2005).

    4. Park, S.J., Ahn, Y.J., Oh, S.R., et al. Amyrin attenuates scopolamine-induced cognitive impairment in mice. Biol. Pharm. Bull. 37(7), 1207-1213 (2014).

    5. Ferraz-Filha, Z.S., de Paula Michel Araújo, M.C., Ferrari, F.C., et al. Tabebuia roseoalba: In vivo hypouricemic and anti-inflammatory effects of its ethanolic extract and constituents. Planta Med. 82(16), 1395-1402 (2016).