A phospholipid
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1,2-Dilinoleoyl-sn-glycero-3-PC

Item No. 20954

Technical Information
Formal Name
(7R,18Z,21Z)-4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]oxy]-trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, inner salt, 4-oxide
CAS Number
998-06-1
Synonyms
  • 1,2-Dilinoleoyl-sn-glycero-3-Phosphocholine
  • DLPC
  • 18:2 (cis) PC
Molecular Formula
C44H80NO8P
Formula Weight
Purity
≥95%
A 100 mg/ml solution in ethanol
Ethanol: 25 mg/ml
λmax
231 nm
SMILES
O=P(OCC[N+](C)(C)C)([O-])OC[C@H](OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCC/C=C\C/C=C\CCCCC)=O
InChi Code
InChI=1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h14-17,20-23,42H,6-13,18-19,24-41H2,1-5H3/b16-14-,17-15-,22-20-,23-21-/t42-/m1/s1
InChi Key
FVXDQWZBHIXIEJ-LNDKUQBDSA-N
Side Chain Carbon Sum
36:4
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    Learn More About Leveraging Helper Lipids to Achieve Versatile LNPs
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    Product Description

    1,2-Dilinoleoyl-sn-glycero-3-PC is a phospholipid containing the polyunsaturated long-chain (18:2) linoleic acid inserted at the sn-1 and sn-2 positions. It can be used to generate micelles, liposomes, and other types of artificial membranes.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ritter, M., Schmidt, S., Jakab, M., et alEvidence for the formation of symmetric and asymmetric DLPC-DAPC lipid bilayer domains. Cell. Physiol. Biochem. 32(1), 46-52 (2013).

    2. Mazari, A., Iwamoto, S., and Yamauchi, R. Effects of linoleic acid position in phosphatidylcholines and cholesterol addition on their rates of peroxidation in unilamellar liposomes. Biosci. Biotechnol. Biochem. 74(5), 1013-1017 (2010).

    3. Bagatolli, L.A., and Gratton, E. A correlation between lipid domain shape and binary phospholipid mixture composition in free standing bilayers: A two-photon fluorescence microscopy study. Biophys. J. 79(1), 434-447 (2000).