A phospholipid
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1,2-Dioleoyl-sn-glycero-3-PA (ammonium salt)

Item No. 20956

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(R)-2,3-bis(oleoyloxy)propyl hydrogen phosphate, monoammonium salt
Synonyms
  • 1,2-Dioctadecenoyl-sn-glycero-3-PA
  • 1,2-Dioctadecenoyl-sn-glycero-3-phosphatidic Acid
  • 1,2-Dioleoyl-sn-glycero-3-phosphate
  • 1,2-Dioleoyl-sn-glycero-3-phosphatidic Acid
  • 1,2-DOPA
  • 18:1/18:1-PA
  • PA(18:1/18:1)
Molecular Formula
C39H72O8P • NH4
Formula Weight
718.0
Purity
≥95%
Formulation (Request formulation change)
A 5 mg/ml solution in chloroform
Solubility(Learn about Variance in Solubility)
Chloroform: 20 mg/ml
SMILES
CCCCCCCC/C=C\CCCCCCCC(O[C@@H](COP(O)([O-])=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O.[NH4+]
InChi Code
InChI=1S/C39H73O8P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)45-35-37(36-46-48(42,43)44)47-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,37H,3-16,21-36H2,1-2H3,(H2,42,43,44);1H3/b19-17-,20-18-;/t37-;/m1./s1
InChi Key
PEZDINNCNWFVEL-ZBFGHDQJSA-N
Side Chain Carbon Sum
36:2
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    500 µg

    $75

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    1 mg

    $143

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    5 mg

    $589

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    Cayman Chemical
    Learn More About Leveraging Helper Lipids to Achieve Versatile LNPs
    READ THE ARTICLE
    Product Description

    1,2-Dioleoyl-sn-glycero-3-PA (DOPA) is a phospholipid containing the long-chain (18:1) fatty acid oleic acid (Item Nos. 90260 | 24659) inserted at the sn-1 and sn-2 positions. It has been used in the generation of micelles, liposomes, and other artificial membranes.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Takahashi, T., Nomura, F., Yokoyama, Y., et al. Multiple membrane interactions and versatile vesicle deformations elicited by melittin. Toxins (Basel) 5(4), 637-664 (2013).

    2. Vequi-Suplicy, C.C., Riske, K.A., Knorr, R.L., et al. Vesicles with charged domains. Biochim. Biophys. Acta 1798(7), 1338-1347 (2010).