A histamine H1 receptor antagonist
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Brompheniramine (maleate)

Item No. 20996

Technical Information
Formal Name
γ-(4-bromophenyl)-N,N-dimethyl-2-pyridinepropanamine, 2Z-butenedioate
CAS Number
980-71-2
Synonyms
  • (±)-Brompheniramine
Molecular Formula
C16H19BrN2 • C4H4O4
Formula Weight
Purity
≥95%
Formulation
A crystalline solid
DMF: 15 mg/mlDMSO: 10 mg/mlEthanol: 5 mg/mlPBS (pH 7.2): 5 mg/ml
λmax
261 nm
SMILES
CN(C)CCC(C1=CC=C(Br)C=C1)C2=CC=CC=N2.OC(/C=C\C(O)=O)=O
InChi Code
InChI=1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChi Key
SRGKFVAASLQVBO-BTJKTKAUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Brompheniramine is a first generation antihistamine of the propylamine class. It antagonizes histamine H1 receptors (Ki = 6.06 nM) and also inhibits the reuptake of serotonin and norepinephrine.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Cusack, B., Nelson, A., and Richelson, E. Binding of antidepressants to human brain receptors: Focus on newer generation compounds. Psychopharmacology (Berl.) 114(4), 559-565 (1994).

    2. Högberg, T., Ulff, B., Renyi, A.L., et alSynthesis of pyridylallylamines related to zimelidine and their inhibition of neuronal monoamine uptake. J. Med. Chem. 24(12), 1499-1507 (1981).