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(-)-Altenuene

Item № 21130
CAS № 889101-41-1
Purity ≥98%
product image
                (CAS 889101-41-1)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 mg $675.00 0.00

Pricing updated 2019-06-15. Prices are subject to change without notice.

Description

(-)-Altenuene is a natural mycotoxin that was first isolated from A. tenuis. It has antioxidant activity and inhibits cholinesterases.1 Unlike tenuazonic acid (Item No. 11443), (-)-altenuene does not display toxicity as assessed by the chicken embryo assay.2 (-)-Altenuene does not display significant topoisomerase inhibitory activity, unlike alternariol (Item No. 11306).3

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Technical Information
Formal Name
2R,3R,4aR,4a-tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one
CAS Number
889101-41-1
Molecular Formula
C15H16O6
Formula Weight
292.3
Purity
≥98%
Formulation
A powder
SMILES
O=C1C2=C(O)C=C(OC)C=C2C3=C[C@@H](O)[C@H](O)C[C@@]3(C)O1
InChI Code
InChI=1S/C15H16O6/c1-15-6-12(18)10(16)5-9(15)8-3-7(20-2)4-11(17)13(8)14(19)21-15/h3-5,10,12,16-18H,6H2,1-2H3/t10-,12-,15-/m1/s1
InChI Key
MMHTXEATDNFMMY-IXPVHAAZSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Bhagat, J., Kaur, A., Kaur, R., et al. Cholinesterase inhibitor (Altenuene) from an endophytic fungus Alternaria alternata: Optimization, purification and characterization J. Appl. Microbiol. 121(4), 1015-1025 (2016).

2. Griffin, G.F., and Chu, F.S. Toxicity of the Alternaria metabolites alternariol, alternariol methyl ether, altenuene, and tenuazonic acid in the chicken embryo assay Applied and Environmental Microbiology 46(6), 1420-1422 (1983).

3. Fehr, M., Pahlke, G., Fritz, J.E., et al. Alternariol acts as a topoisomerase poison, preferentially affecting the IIα isoform Mol. Nutr. Food Res. 53(4), 441-451 (2008).

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