Pricing updated 2019-01-15. Prices are subject to change without notice.
(-)-Altenuene is a natural mycotoxin that was first isolated from A. tenuis. It has antioxidant activity and inhibits cholinesterases.1 Unlike tenuazonic acid (Item No. 11443), (-)-altenuene does not display toxicity as assessed by the chicken embryo assay.2 (-)-Altenuene does not display significant topoisomerase inhibitory activity, unlike alternariol (Item No. 11306).3
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1. Bhagat, J., Kaur, A., Kaur, R., et al. Cholinesterase inhibitor (Altenuene) from an endophytic fungus Alternaria alternata: Optimization, purification and characterization J. Appl. Microbiol. 121(4), 1015-1025 (2016).
2. Griffin, G.F., and Chu, F.S. Toxicity of the Alternaria metabolites alternariol, alternariol methyl ether, altenuene, and tenuazonic acid in the chicken embryo assay Applied and Environmental Microbiology 46(6), 1420-1422 (1983).
3. Fehr, M., Pahlke, G., Fritz, J.E., et al. Alternariol acts as a topoisomerase poison, preferentially affecting the IIα isoform Mol. Nutr. Food Res. 53(4), 441-451 (2008).