A polyphenol
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Oleuropein

Item No. 21220

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2S,3E,4S)-3-ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4-acetic acid, 2-(3,4-dihydroxyphenyl)ethyl ester
CAS Number
32619-42-4
Molecular Formula
C25H32O13
Formula Weight
540.5
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 50 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 0.25 mg/ml
λmax
234, 283 nm
SMILES
O[C@H]1[C@H](O)[C@@H](CO)O[C@](O[C@H]2/C([C@H](CC(OCCC3=CC=C(O)C(O)=C3)=O)C(C(OC)=O)=CO2)=C/C)([H])[C@@H]1O
InChi Code
InChI=1S/C25H32O13/c1-3-13-14(9-19(29)35-7-6-12-4-5-16(27)17(28)8-12)15(23(33)34-2)11-36-24(13)38-25-22(32)21(31)20(30)18(10-26)37-25/h3-5,8,11,14,18,20-22,24-28,30-32H,6-7,9-10H2,1-2H3/b13-3+/t14-,18+,20+,21-,22+,24-,25-/m0/s1
InChi Key
RFWGABANNQMHMZ-ZCHJGGQASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $63

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    50 mg

    $105

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    100 mg

    $171

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    500 mg

    $481

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    Cayman Chemical
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    Product Description

    Oleuropein is a polyphenol that is abundant in olive leaves and fruits. Like many polyphenols, oleuropein exhibits antioxidant and free radical-scavenging activities, resulting in a wide range of cellular and physiological effects.1 Oleuropein reduces adipogenesis by antagonizing PPARγ and induces autophagy by activating AMPK.2 It inhibits proliferation and induces apoptosis in cancer cells but not normal cells.3 Oleuropein also has bone-protecting effects in mice and rats.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Umeno, A., Horie, M., Murotomi, K., et al. Antioxidative and antidiabetic effects of natural polyphenols and isoflavones. Molecules 21(6), E708 (2016).

    2. Rigacci, S., and Stefani, M. Nutraceutical properties of olive oil Polyphenols. An itinerary from cultured cells through animal models to humans. Int. J. Mol. Sci. 17(6), E843 (2016).

    3. Boss, A., Bishop, K.S., Marlow, G., et al. Evidence to support the anti-cancer effect of olive leaf extract and future directions. Nutrients 8(8), E513 (2016).

    4. Chin, K.Y., and Ima-Nirwana, S. Olives and bone: A green osteoporosis prevention option. Int. J. Environ. Res. Public Health 13(8), E755 (2016).