An Analytical Reference Standard
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Parent Compound(s)
9000324Spironolactone
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Canrenone

Item No. 21307

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Aldadiene
  • NSC 261713
  • SC-9376
  • SC-14266
Technical Information
Formal Name
17α-hydroxy-3-oxo-pregna-4,6-diene-21-carboxylic acid γ-lactone
CAS Number
976-71-6
Molecular Formula
C22H28O3
Formula Weight
340.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS(pH 7.2) (1:4): 0.2 mg/mlEthanol: 10 mg/ml
λmax
210, 281 nm
SMILES
O=C(CC1)O[C@@]21CC[C@@]3([H])[C@]4([H])C=CC5=CC(CC[C@]5(C)[C@@]4([H])CC[C@@]32C)=O
InChi Code
InChI=1S/C22H28O3/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21)12-8-19(24)25-22/h3-4,13,16-18H,5-12H2,1-2H3/t16-,17+,18+,20+,21+,22-/m1/s1
InChi Key
UJVLDDZCTMKXJK-WNHSNXHDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Canrenone (Item No. 21307) is an analytical reference standard categorized as a steroid.1 It is an active metabolite of spironolactone (Item No. 9000324) that acts as a diuretic. Diuretics, including canrenone, have been abused as performance-enhancing drugs and masking agents in sports doping.2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Larik, F.A., Saaed, A., Shahzad, D., et al. Synthetic approaches towards the multi target drug spironolactone and its potent analogues/derivatives. Steroids 118, 76-92 (2017).

    2. Cadwallader, A.B., de la Torre, X., Tieri, A., et al. The abuse of diuretics as performance-enhancing drugs and masking agents in sport doping: Pharmacology, toxicology and analysis. Br. J. Pharmacol. 161(1), 1-16 (2010).