A conditionally essential nutrient
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L-Carnitine

Item No. 21489

Technical Information
Formal Name
3-carboxy-2R-hydroxy-N,N,N-trimethyl-1-propanaminium, inner salt
CAS Number
541-15-1
Synonyms
  • (–)-Carnitine
  • Levocarnitine
  • R-Carnitine
Molecular Formula
C7H15NO3
Formula Weight
Purity
≥95%
A crystalline solid
Ethanol: 10 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
[O-]C(C[C@@H](O)C[N+](C)(C)C)=O
InChi Code
InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
InChi Key
PHIQHXFUZVPYII-ZCFIWIBFSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    L-Carnitine is a conditionally essential nutrient.1 It is obtained from dietary sources or through the metabolism of lysine and methionine.2,3 L-Carnitine facilitates the transport of long-chain fatty acids into the mitochondrial matrix for β-oxidation, has other diverse roles on metabolism, and is involved in the maintenance of coenzyme A (CoA; Item No. 16147) stores. Plasma and/or tissue levels of L-carnitine are decreased in primary L-carnitine deficiency, a disorder characterized by impaired fatty acid oxidation, with symptoms varying depending on whether it is systemic or muscle-specific.1 Serum and tissue levels of L-carnitine are also reduced in secondary L-carnitine deficiencies caused by a variety of hereditary defects or acquired disorders.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Seim, H., Eichler, K., and Kleber, H.-P. L(–)-Carnitine and its precursor, γ-butyrobetaine. Nutraceuticals in health and disease prevention 217-256 (2001).

    2. Vaz, F.M., and Wanders, R.J.A. Carnitine biosynthesis in mammals. Biochem. J. 361(Pt 3), 417-429 (2002).

    3. Fu, L., Huang, M., and Chen, S. Primary carnitine deficiency and cardiomyopathy. Korean. Circ. J. 43(12), 785-792 (2013).

    Product Citations

    Bernardi, F., Torrejon, J., Basili, I., et alMultiomic integration reveals tumoral hererogeneity of lipid dependence within lethal group 3 medulloblastoma. Cell 44, 383-404 (2026).