An esterified form of diclofenac
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Diclofenac ethyl ester

Item No. 22105

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[(2,6-dichlorophenyl)amino]-benzeneacetic acid, ethyl ester
CAS Number
15307-77-4
Molecular Formula
C16H15Cl2NO2
Formula Weight
324.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10mg/mLDMF:PBS (pH 7.2) (1:3): 0.25mg/mLDMSO: 5mg/mL
λmax
229, 243, 281 nm
SMILES
ClC1=C(N([H])C2=C(CC(OCC)=O)C=CC=C2)C(Cl)=CC=C1
InChi Code
InChI=1S/C16H15Cl2NO2/c1-2-21-15(20)10-11-6-3-4-9-14(11)19-16-12(17)7-5-8-13(16)18/h3-9,19H,2,10H2,1H3
InChi Key
YPBCAMNSNFVYQL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    25 mg

    $90

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    50 mg

    $168

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    100 mg

    $315

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    250 mg

    $696

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    Product Description

    Diclofenac ethyl ester is an esterified form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac (Item Nos. 22983 | 70680). It has been used as a precursor in the synthesis of diclofenac derivatives with anti-inflammatory and analgesic activity and decreased ulcerogenicity.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Amir, M., Akhter, W., and Somakala, K. Synthesis of furoxan derivatives of diclofenac as potent anti-inflammatory agents with reduced GI toxicity. Indian J. Chem. 55(B), 989-998 (2016).

    2. Bhandari, S.V., Bothara, K.G., Raut, M.K., et al. Design, synthesis and evaluation of antiinflammatory, analgesic and ulcerogenicity studies of novel S-substituted phenacyl-1,3,4-oxadiazole-2-thiol and Schiff bases of diclofenac acid as nonulcerogenic derivatives. Bioorg. Med. Chem. 16(4), 1822-1831 (2008).