A prodrug form of diclofenac
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Diclofenac methyl ester

Item No. 22218

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[(2,6-dichlorophenyl)amino]-benzeneacetic acid, methyl ester
CAS Number
15307-78-5
Synonyms
  • Methanol Diclofenac ester
Molecular Formula
C15H13Cl2NO2
Formula Weight
310.2
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMF:PBS (pH 7.2) (1:3): 0.25 mg/mlDMSO: 5 mg/ml
λmax
276 nm
SMILES
ClC1=C(N([H])C2=C(CC(OC)=O)C=CC=C2)C(Cl)=CC=C1
InChi Code
InChI=1S/C15H13Cl2NO2/c1-20-14(19)9-10-5-2-3-8-13(10)18-15-11(16)6-4-7-12(15)17/h2-8,18H,9H2,1H3
InChi Key
VETACGBDFVVKGZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    10 mg

    $49

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    50 mg

    $213

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    100 mg

    $329

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    Product Description

    Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac (Item Nos. 70680 | 22983).1 It is more soluble than diclofenac acid in isopropylmyristate. Diclofenac methyl ester does not permeate human epidermal membranes in vitro.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lobo, S., Li, H., Farhan, N., et al. Evaluation of diclofenac prodrugs for enhancing transdermal delivery. Drug Dev. Ind. Pharm. 40(3), 425-432 (2014).