An isomer and metabolite of propranolol
Related Products
Parent Compound(s)
23349(±)-Propranolol (hydrochloride)
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rac-7-hydroxy Propranolol (hydrochloride)

Item No. 22380

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
8-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-2-naphthalenol, monohydrochloride
CAS Number
76275-67-7
Synonyms
  • (±)-7-hydroxy Propranolol
Molecular Formula
C16H21NO3 • HCl
Formula Weight
311.8
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
SMILES
OC1=CC2=C(OCC(CNC(C)C)O)C=CC=C2C=C1.Cl
InChi Code
InChI=1S/C16H21NO3.ClH/c1-11(2)17-9-14(19)10-20-16-5-3-4-12-6-7-13(18)8-15(12)16;/h3-8,11,14,17-19H,9-10H2,1-2H3;1H
InChi Key
PCNYXMBZFXLWCG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

    $169

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    1 mg

    $303

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    Product Description

    rac-7-hydroxy Propranolol (hydrochloride) is a ring-hydroxylated isomer and metabolite of (±)-propranolol (Item No. 23349) that is an antagonist at β-adrenergic receptors (0.95 potency relative to propranolol).1 It also demonstrates potent vasodilator activity (0.20 potency relative to propranolol; pA2 = 7.58).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Oatis, J.E., Jr., Russell, M.P., Knapp, D.R., et al. Ring-hydroxylated propranolol: Synthesis and β-receptor antagonist and vasodilating activities of the seven isomers. J. Med. Chem. 24(3), 309-314 (1981).