A long-chain ceramide-1-phosphate
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C16 Ceramide-1-phosphate (d18:1/16:0) (ammonium salt)

Item No. 22542

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(1S,2R,3E)-2-hydroxy-1-[(phosphonooxy)methyl]-3-heptadecen-1-yl]-hexadecanamide, monoammonium salt
CAS Number
1246303-22-9
Synonyms
  • C16 C1P
  • C16 Ceramide-1-phosphate
  • Ceramide-1-phosphate (d18:1/16:0)
  • CerP(d18:1/16:0)
Molecular Formula
C34H67NO6P • NH4
Formula Weight
634.9
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Chloroform:Methanol:NH4OH (80:20:2): Soluble
SMILES
O[C@H](/C=C/CCCCCCCCCCCCC)[C@@H](NC(CCCCCCCCCCCCCCC)=O)COP(O)([O-])=O.[NH4+]
InChi Code
InChI=1S/C34H68NO6P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(36)32(31-41-42(38,39)40)35-34(37)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h27,29,32-33,36H,3-26,28,30-31H2,1-2H3,(H,35,37)(H2,38,39,40);1H3/b29-27+;/t32-,33+;/m0./s1
InChi Key
RCRVTEZMCBPWGN-YWBCJBABSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

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    Product Description

    C16 Ceramide-1-phosphate (C16 C1P) is one of the main forms of C1P found in cells.1 It is created by phosphorylation of C16 ceramide (Item No. 10681) by ceramide kinase. C16 C1P activates cytosolic phospholipase A2α (PLA2α) and stimulates the release of arachidonic acid (Item No. 90010 | 10006607) in A549 cells.2 [Matreya, LLC. Catalog No. 2046]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lamour, N.F., Stahelin, R.V., Wijesinghe, D.S., et al. Ceramide kinase uses ceramide provided by ceramide transport protein: Localization to organelles of eicosanoid synthesis. J. Lipid Res. 48(6), 1293-1304 (2007).

    2. Wijesinghe, D.S., Subramanian, P., Lamour, N.F., et al. Chain length specificity for activation of cPLA2alpha by C1P: Use of the dodecane delivery system to determine lipid-specific effects. J. Lipid Res. 50(10), 1986-1995 (2009).