Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
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Item No. 22830

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C6 NBD galactosylceramide is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C6 nitrobenzoxadiazole (C6 NBD; Item No. 18871) group.1 C6 NBD galactosylceramide has been used to study intracellular localization and metabolism of galactosylceramide, a sphingolipid whose synthesis is disrupted in Krabbe disease due to a deficiency of galactosylceramide β-galactosidase.1,2,3 As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1621]
WARNING This product is not for human or veterinary use.
1. Sphingolipid metabolism in cultured fibroblasts: Microscopic and biochemical studies employing a fluorescent ceramide analogue. Proc. Natl. Acad. Sci. USA 80(9), 2608-2612 (1983).
2. Sorting of sphingolipids in the endocytic pathway of HT29 cells. J. Cell. Biol. 114(2), 231-239 (1991).
3. Role of endogenous psychosine accumulation in oligodendrocytes differentiation and survival: Implication for Krabbe disease. Brain Res. 1508, 44-52 (2013).