A xylazine metabolite
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4-hydroxy Xylazine

Item No. 22920

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[(5,6-dihydro-4H-1,3-thiazin-2-yl)amino]-3,5-dimethyl-phenol
CAS Number
145356-32-7
Synonyms
  • 4-Hydroxyxylazine
  • p-hydroxy Xylazine
  • para-hydroxy Xylazine
Molecular Formula
C12H16N2OS
Formula Weight
236.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly SolubleMethanol: Slightly Soluble
SMILES
CC1=CC(O)=CC(C)=C1NC2=NCCCS2
InChi Code
InChI=1S/C12H16N2OS/c1-8-6-10(15)7-9(2)11(8)14-12-13-4-3-5-16-12/h6-7,15H,3-5H2,1-2H3,(H,13,14)
InChi Key
FXWQWFCVDXMJNM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $116

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    1 mg

    $220

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    5 mg

    $867

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    Product Description

    4-hydroxy Xylazine is a metabolite of xylazine (Item No. 14113).1 Xylazine is an agonist of α2-adrenergic receptors used for sedation, anesthesia, and analgesia in non-human mammals.2,3,4 4-hydroxy Xylazine has been used as a marker for xylazine doping in MS analysis of equine urine.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Spyrodaki, M.-H., Lyris, E., Georgoulakis, I., et al. Determination of xylazine and its metabolites by GC-MS in equine urine for doping analysis. J. Pharm. Biomed. Anal. 35(1), 107-116 (2004).

    2. Virtanen, R., Savola, J.M., Saano, V., et al. Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonist. Eur. J. Pharmacol. 150(1-2), 9-14 (1988).

    3. Richardson, C.A., and Flecknell, P.A. Anaesthesia and post-operative analgesia following experimental surgery in laboratory rodents: Are we making progress? Altem. Lab. Anim. 33(2), 119-127 (2005).

    4. Vallverde, A. Alpha-2 agonists as pain therapy in horses. Vet. Clin. North Am. Equine Pract. 26(3), 515-532 (2010).