An α2-adrenergic receptor agonist
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Xylazine (hydrochloride)

Item No. 36692

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine, monohydrochloride
CAS Number
23076-35-9
Synonyms
  • BAY-Va 1470
Molecular Formula
C12H16N2S • HCl
Formula Weight
256.8
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 50 mg/ml
λmax
212 nm
SMILES
CC1=C(C(C)=CC=C1)NC2=NCCCS2.Cl
InChi Code
InChI=1S/C12H16N2S.ClH/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;/h3,5-6H,4,7-8H2,1-2H3,(H,13,14);1H
InChi Key
QYEFBJRXKKSABU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 mg

    $29

    Add

    1 g

    $51

    Add

    5 g

    $169

    Add
    Product Description

    Xylazine is an agonist of α2-adrenergic receptors (Ki = 194 nM).1 It is an analog of clonidine, an α2-adrenergic receptor agonist used to reduce blood pressure. Xylazine is used for sedation, anesthesia, and analgesia in non-human mammals.2,3 This product is also available as an analytical reference standard (Item Nos. 37854 | 22641).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Virtanen, R., Savola, J.M., Saano, V., et al. Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonist. Eur. J. Pharmacol. 150(1-2), 9-14 (1988).

    2. Richardson, C.A., and Flecknell, P.A. Anaesthesia and post-operative analgesia following experimental surgery in laboratory rodents: Are we making progress? Altem. Lab. Anim. 33(2), 119-127 (2005).

    3. Vallverde, A. Alpha-2 agonists as pain therapy in horses. Vet. Clin. North Am. Equine Pract. 26(3), 515-532 (2010).

    Product Citations

    Kang, J., Xu, R., Lee, S., et al. Discovery, structural characterization, and preclinicla evaluation of monoclonal antibodies against xylazine poisoning. ACS Pharmacol. Transl. Sci. (2026).