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Discover high-quality research tools to investigate GLP-1 mechanisms and next-generation metabolic targets.
OBESITY RESEARCH SOLUTIONSAdvanced glycation end products (AGEs) are formed from the nonenzymatic reaction of amino groups with reducing sugars.1,2,3 AGEs have been implicated in diseases, such as diabetes mellitus, non-diabetic nephropathy, macrovascular disease, Alzheimer’s disease, cataract, and ageing.1,2,3 AGE receptors, such as the receptor for AGE (RAGE), mediate biological responses to AGEs, including endocytic uptake and degradation and induction of cytokines and growth factors.1,2,3 AGE-BSA (Glycoaldehyde modified) was produced by incubating BSA with glycolaldehyde, followed by extensive dialysis.
WARNING This product is not for human or veterinary use.
1. Advanced glycation end-
2. Oxidative stress and diabetic complications. Circ. Res. 107(9), 1058-1070 (2010).
3. Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): An overview of their mechanisms of formation. Free Radic. Res. 47(Suppl 1), 3-27 (2013).