Albumin isolated from bovine plasma and modified by carboxymethylation
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AGE-BSA (Carboxymethyl modified)

Item No. 22972

Technical Information
Synonyms
  • Nε-(1-Carboxymethyl)-L-lysine – Bovine Serum Albumin
  • Nε-(1-Carboxymethyl)-L-lysine -BSA
Source
Albumin isolated from bovine plasma and modified by carboxymethylation
MW
69.3 kDa
Lyophilized from a solution in PBS, pH 7.4, 200 μg per vial. Reconstitution with 0.2 ml of water will yield 1 mg/ml solution in 1X PBS.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Advanced glycation end products (AGEs) are formed from the nonenzymatic reaction of amino groups with reducing sugars.1,2,3 AGEs have been implicated in diseases, such as diabetes mellitus, non-diabetic nephropathy, macrovascular disease, Alzheimer’s disease, cataract, and ageing. 1,2,3 AGE receptors, such as the receptor for AGE (RAGE), mediate biological responses to AGEs, including endocytic uptake and degradation and induction of cytokines and growth factors.1,2,3 AGE-BSA (Carboxymethyl modified) was produced by incubating BSA with glyoxylic acid and sodium cyanoborohydride.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Singh, R., Barden, A., Mori, T., et alAdvanced glycation end-products: A review. Diabetologia 44(2), 129-146 (2001).