A glycosaminoglycan
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

D-Glucosamine-6-sulfate

Item No. 23097

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-amino-2-deoxy-D-glucose 6-(hydrogen sulfate)
CAS Number
91674-26-9
Synonyms
  • GlcN-6S
Molecular Formula
C6H13NO8S
Formula Weight
259.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 0.5 mg/mLDMSO: 2 mg/mLPBS (pH 7.2): 5.0 mg/mL
SMILES
N[C@H]([C@@H](O)[C@H](O)[C@H](O)COS(O)(=O)=O)C=O
InChi Code
InChI=1S/C6H13NO8S/c7-3(1-8)5(10)6(11)4(9)2-15-16(12,13)14/h1,3-6,9-11H,2,7H2,(H,12,13,14)/t3-,4+,5+,6+/m0/s1
InChi Key
KRCSEEITTBNSQS-SLPGGIOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    10 mg

    $44

    Add

    50 mg

    $195

    Add

    100 mg

    $344

    Add

    250 mg

    $748

    Add
    Kinase Resource Center
    Discover Products & Resources for Kinase Research
    • Kinase inhibitors, screening libraries, assay kits, & more
    • Tools to study kinase signaling pathways:
      • Growth factor signaling
      • PI3K/Akt/mTOR
      • MAPKs (ERK, p38, & JNK)
      • JAK/STAT signaling
    • Articles, resources, & advice
    EXPLORE NOW
    Product Description

    D-Glucosamine-6-sulfate is a naturally occurring glycosaminoglycan.1 It activates the glmS ribozyme from B. subtilis, a Gram-positive bacterium, when used at a concentration of 200 µM.2 It has been used to form polyvalent dendrimer conjugates that inhibit angiogenesis and endothelial cell proliferation induced by FGF-2 in vitro and prevent scar tissue formation in a rabbit model of glaucoma surgery.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Foot, M., and Mulholland, M. Classification of chondroitin sulfate A, chondroitin sulfate C, glucosamine hydrochloride and glucosamine 6 sulfate using chemometric techniques. J. Pharm. Biomed. Anal. 38(3), 397-407 (2005).

    2. Roth, A., Nahvi, A., Lee, M., et al. Characteristics of the glmS ribozyme suggest only structural roles for divalent metal ions. RNA 12(4), 607-619 (2006).

    3. Shaunak, S., Thomas, S., Gianasi, E., et al. Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation. Nat. Biotechnol. 22(8), 977-984 (2004).