A glycosaminoglycan
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D-Glucosamine-6-sulfate

Item No. 23097

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-amino-2-deoxy-D-glucose 6-(hydrogen sulfate)
CAS Number
91674-26-9
Synonyms
  • GlcN-6S
Molecular Formula
C6H13NO8S
Formula Weight
259.2
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 0.5 mg/mLDMSO: 2 mg/mLPBS (pH 7.2): 5.0 mg/mL
SMILES
N[C@H]([C@@H](O)[C@H](O)[C@H](O)COS(O)(=O)=O)C=O
InChi Code
InChI=1S/C6H13NO8S/c7-3(1-8)5(10)6(11)4(9)2-15-16(12,13)14/h1,3-6,9-11H,2,7H2,(H,12,13,14)/t3-,4+,5+,6+/m0/s1
InChi Key
KRCSEEITTBNSQS-SLPGGIOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

    $44

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    50 mg

    $195

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    100 mg

    $344

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    250 mg

    $748

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    Product Description

    D-Glucosamine-6-sulfate is a naturally occurring glycosaminoglycan.1 It activates the glmS ribozyme from B. subtilis, a Gram-positive bacterium, when used at a concentration of 200 µM.2 It has been used to form polyvalent dendrimer conjugates that inhibit angiogenesis and endothelial cell proliferation induced by FGF-2 in vitro and prevent scar tissue formation in a rabbit model of glaucoma surgery.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Foot, M., and Mulholland, M. Classification of chondroitin sulfate A, chondroitin sulfate C, glucosamine hydrochloride and glucosamine 6 sulfate using chemometric techniques. J. Pharm. Biomed. Anal. 38(3), 397-407 (2005).

    2. Roth, A., Nahvi, A., Lee, M., et al. Characteristics of the glmS ribozyme suggest only structural roles for divalent metal ions. RNA 12(4), 607-619 (2006).

    3. Shaunak, S., Thomas, S., Gianasi, E., et al. Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation. Nat. Biotechnol. 22(8), 977-984 (2004).