A terpene with diverse biological activities
Related Products
Isomer(s)
33831Carveol
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

(1R)-(+)-Camphor

Item No. 23175

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(1R,4R)-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one
CAS Number
464-49-3
Synonyms
  • (+)-Camphor
  • (R)-Camphor
Molecular Formula
C10H16O
Formula Weight
152.2
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Water: 1.2 mg/ml
SMILES
O=C1C[C@H]2CC[C@@]1(C2(C)C)C
InChi Code
InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m1/s1
InChi Key
DSSYKIVIOFKYAU-XCBNKYQSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 mg

    $50

    Add

    1 g

    $75

    Add
    Cayman Chemical
    Visit Our Environmental Toxicology Resource Center

    Explore additional resources to study natural toxins, pollutants including PFAS and 6-PPD-Q, and their biological effects.

    ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICES
    Product Description

    (1R)-(+)-Camphor is a terpene that has been found in C. sativa, C. indica, and C. sativa/C. indica hybrid strains as well as the essential oils from a variety of herbs including rosemary, lavender, and sage and has diverse biological activities.1,2,3,4,5,6 It inhibits norepinephrine secretion and cytosolic calcium and sodium increases induced by the nicotinic acetylcholine receptor (nAChR) agonist 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP) in chromaffin cells (IC50s = 70, 88, and 19 μM, respectively).2 (1R)-(+)-Camphor (65-260 μM) induces proliferation of and increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in human primary dermal fibroblasts.3 In vivo, (1R)-(+)-camphor increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in skin in UV-exposed mice when administered at doses of 26 and 55 mM in drinking water post UV-exposure. It reduces cough frequency in citric acid-challenged guinea pigs.4 (1R)-(+)-Camphor is insecticidal, reducing digging activity and inducing mortality of fire ant workers.5 It has also been used as a building block in the synthesis of cannabinergic ligands.6

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Elzinga, S., Fischedick, J., Podkolinski, R., et al. Cannabinoids and terpenes as chemotaxonomic markers in Cannabis. Nat. Prod. Chem. Res. 3(4), 181 (2015).

    2. Park, T.-J., Seo, H.-K., Kang, B.-J., et al. Noncompetitive inhibition by camphor of nicotinic acetylcholine receptors. Biochem. Pharmacol. 61(7), 787-793 (2001).

    3. Tran, T.A., Ho, M.T., Song, Y.W., et al. Camphor induces proliferative and anti-senescence activities in human primary dermal fibroblasts and inhibits UV-induced wrinkle formation in mouse skin. Phytother. Res. 29(12), 1917-1925 (2015).

    4. Laude, E.A., Morice, A.H., and Grattan, T.J. The antitussive effects of menthol, camphor and cineole in conscious guinea-pigs. Pulm. Pharmacol. 7(3), 179-184 (1994).

    5. Zhang, N., Tang, L., Hu, W., et al. Insecticidal, fumigant, and repellent activities of sweet wormwood oil and its individual components against red imported fire ant workers (Hymenoptera: Formicidae). J. Insect Sci. 14(1), pii:241 (2014).

    6. Lu, D., Guo, J., Duclos, R.I., Jr., et al. Bornyl- and isobornyl-Δ8-tetrahydrocannabinols: A novel class of cannabinergic ligands. J. Med. Chem. 51(20), 6393-6399 (2008).