A monoterpene alcohol
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Isoborneol

Item No. 23177

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(1R,2R,4R)-rel-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-ol
CAS Number
124-76-5
Synonyms
  • (±)-Isoborneol
  • DL-Isoborneol
  • Isobornyl Alcohol
  • NSC 26350
Molecular Formula
C10H18O
Formula Weight
154.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMF:PBS (pH 7.2) (1:2): 0.33 mg/mlDMSO: 15 mg/mlEthanol: 15 mg/ml
SMILES
C[C@]1(C2(C)C)CC[C@@H]2C[C@H]1O
InChi Code
InChI=1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8-,10+/m1/s1
InChi Key
DTGKSKDOIYIVQL-MRTMQBJTSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 g

    $36

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    Product Description

    Isoborneol is a monoterpene alcohol that has been found in a variety of plants, including C. sativa, C. indica, and C. sativa/C. indica hybrid strains, with neuroprotective and antiviral activities.1,2,3 It reduces SH-SY5Y cell death induced by 6-OHDA (Item No. 25330) when used at concentrations ranging from 2.5 to 10 μM via inhibition of apoptosis, reducing increases in intracellular levels of reactive oxygen species (ROS), and preventing decreases in the mitochondrial membrane potential.2 Isoborneol (0.03 and 0.06%) reduces HSV-1 viral replication by inhibiting viral protein synthesis.3 It inhibits the glycosylation of HSV-1 glycoprotein gB but has no effect on protein glycosylation in Vero cells.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Elzinga, S., Fischedick, J., Podkolinski, R., et al. Cannabinoids and terpenes as chemotaxonomic markers in Cannabis. Nat. Prod. Chem. Res. 3(4), 181 (2015).

    2. Tian, L.-L., Zhou, Z., Zhang, Q., et al. Protective effect of (±) isoborneol against 6-OHDA-induced apoptosis in SH-SY5Y cells. Cell. Physiol. Biochem. 20(6), 1019-1032 (2007).

    3. Armaka, M., Papanikolaou, E., Sivropoulou, A., et al. Antiviral properties of isoborneol, a potent inhibitor of herpes simplex virus type 1. Antiviral Res. 43(2), 79-92 (1999).