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Caffeic acid-13C3 is an isotopically enriched form of caffeic acid (Item No. 70602) that is intended for use as an internal standard for the quantification of caffeic acid by GC- or LC-MS. Caffeic acid is an inhibitor of 5-LO (Item No. 60402), with IC50 values of 3.7-72 µM, and 12-LO, with IC50 values of 5.1-30 µM.1,2
WARNING This product is not for human or veterinary use.
1. Caffeic acid is a selective inhibitor for leukotriene biosynthesis. Biochim. Biophys. Acta 792(1), 92-97 (1984).
2. Inhibition of arachidonate lipoxygenase activities by 2-