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Active Metabolite(s)
30784JKE-1674
Contained In
35093Cell Death Screening Library (96-Well)
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ML-210

Item No. 23282

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
1360705-96-9
Synonyms
  • DPI10
Formula Weight
475.3
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMF:PBS(pH 7.2)(1:1): 0.5 mg/mlDMSO: 2.5 mg/mlEthanol: slightly soluble
λmax
232 nm
SMILES
ClC1=CC=C(C(C2=CC=C(Cl)C=C2)N3CCN(C(C4=NOC(C)=C4[N+]([O-])=O)=O)CC3)C=C1
InChi Code
InChI=1S/C22H20Cl2N4O4/c1-14-20(28(30)31)19(25-32-14)22(29)27-12-10-26(11-13-27)21(15-2-6-17(23)7-3-15)16-4-8-18(24)9-5-16/h2-9,21H,10-13H2,1H3
InChi Key
VIBHJPDPEVVDTB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $36

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    5 mg

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    10 mg

    $236

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    25 mg

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    Cayman Chemical
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    Product Description

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Nakamura, T., Hipp, C., Mourão, A.S.D., et al. Phase separation of FSP1 promotes ferroptosis. Nature 619, 371-377 (2023).

    Xue, Q., Yan, D., Chen, X., et al. Copper-dependent autophagic degradation of GPX4 drives ferroptosis. Autophagy (2023).

    ­Wang, F., Graham, E.T., Naowarojna, N., et al. PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ. Cell Chem. Bio. 29, 157-170 (2022).

    Mishima, E., Ito, J., Wu, Z., et al. A non-canonical vitamin K cycle is a potent ferroptosis suppressor. Nature 608(7924), 778-783 (2022).

    Nagakannan, P., Islam, M.I., Conrad, M., et al. Cathepsin B is an excutioner of ferroptosis. Biochim. Biophys. Acta Mol. Cell Res. 1868(3), 118928 (2021).

    Wang, W., Green, M., Choi, J.E., et al. CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy. Nature 569(7755), 270-274 (2019).