An herbicide
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Clomazone

Item No. 23298

Technical Information
Formal Name
2-[(2-chlorophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone
CAS Number
81777-89-1
Molecular Formula
C12H14ClNO2
Formula Weight
Purity
≥95%
Formulation
A crystalline solid
DMF: 33 mg/mlDMSO: 16 mg/mlEthanol: 33 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
212 nm
SMILES
ClC1=CC=CC=C1CN2C(C(C)(C)CO2)=O
InChi Code
InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3
InChi Key
KIEDNEWSYUYDSN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Clomazone is an herbicide that reduces chlorophyll and carotenoid levels in plants.1 It is used to control grasses and broad-leaved weeds but is toxic to certain aquatic wildlife with an LC50 of 7.32 mg/L for silver catfish.2 It decreases acetylcholinesterase (AChE) activity in brain and muscle tissue of the silver catfish (83 and 89% inhibition, respectively) when used at concentrations of 5, 10, and 20 mg/L. However, it increases AChE activity in muscle of the teleost fish.3 Formulations containing clomazone have been used as herbicides in agriculture.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kaňa, R., Špundová, M., Ilík, P., et alEffect of herbicide clomazone on photosynthetic processes in primary barley (Hordeum vulgare L.) leaves. Pestic. Biochem. Physiol. 78(3), 161-170 (2004).

    2. dos Santos Miron, D., Crestani, M., Rosa Shettinger, M., et alEffects of the herbicides clomazone, quinclorac, and metsulfuron methyl on acetylcholinesterase activity in the silver catfish (Rhamdia quelen) (Heptapteridae). Ecotoxicol. Environ. Saf. 61(3), 398-403 (2005).

    3. Moraes, B.S., Loro, V.L., Glusczak, L., et alEffects of four rice herbicides on some metabolic and toxicology parameters of teleost fish (Leporinus obtusidens). Chemosphere 68(8), 1597-1601 (2007).