An activator of glycogen phosphorylase b
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

N6-Methyladenosine 5'-monophosphate (sodium salt)

Item No. 23382

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-methyl-5'-adenylic acid, disodium salt
CAS Number
81921-35-9
Synonyms
  • N6-Methyl-AMP
Molecular Formula
C11H14N5O7P • 2Na
Formula Weight
405.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
λmax
210, 266 nm
SMILES
CNC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP([O-])([O-])=O)O3.[Na+].[Na+]
InChi Code
InChI=1S/C11H16N5O7P.2Na/c1-12-9-6-10(14-3-13-9)16(4-15-6)11-8(18)7(17)5(23-11)2-22-24(19,20)21;;/h3-5,7-8,11,17-18H,2H2,1H3,(H,12,13,14)(H2,19,20,21);;/q;2*+1/p-2/t5-,7-,8-,11-;;/m1../s1
InChi Key
HFOKUKRAZPHTHH-LYYWGVPGSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $121

    Add

    10 mg

    $215

    Add

    25 mg

    $448

    Add
    Kinase Resource Center
    Discover Products & Resources for Kinase Research
    • Kinase inhibitors, screening libraries, assay kits, & more
    • Tools to study kinase signaling pathways:
      • Growth factor signaling
      • PI3K/Akt/mTOR
      • MAPKs (ERK, p38, & JNK)
      • JAK/STAT signaling
    • Articles, resources, & advice
    EXPLORE NOW
    Product Description

    N6-Methyladenosine 5'-monophosphate is an activator of glycogen phosphorylase b (Ka = 22 µM).1 It is also a non-competitive inhibitor of rat adenylate kinase II (Ki = 4.2 mM).2 N6-Methyladenosine 5’-monophosphate (sodium salt) has been used for immunoprecipitation of N6-methyladenosine.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Morange, M., García Blanco, F., Vandenbunder, B., et al. AMP Analogs : Their function in the activation of glycogen phosphorylase b. Eur. J. Biochem. 65(2), 553-563 (1976).

    2. Hai, T.T., Picker, D., Abo, M., et al. Species- or isozyme-specific enzyme inhibitors. 7. Selective effects in inhibitions of rat adenylate kinase isozymes by adenosine 5’-phosphate derivatives. J. Med. Chem. 25(7), 806-812 (1982).

    3. Fry, N.J., Law, B.A., Ilkayeva, O.R., et al. N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs. RNA 23(9), 1444-1455 (2017).