A melatonin receptor agonist
Related Products
Labeled Version(s)
31771Tasimelteon-d5
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Tasimelteon

Item No. 23546

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[[(1R,2R)-2-(2,3-dihydro-4-benzofuranyl)cyclopropyl]methyl]-propanamide
CAS Number
609799-22-6
Synonyms
  • BMS 214778
Molecular Formula
C15H19NO2
Formula Weight
245.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/ml
λmax
287 nm
SMILES
O=C(CC)NC[C@@H]1C[C@H]1C2=C3C(OCC3)=CC=C2
InChi Code
InChI=1S/C15H19NO2/c1-2-15(17)16-9-10-8-13(10)11-4-3-5-14-12(11)6-7-18-14/h3-5,10,13H,2,6-9H2,1H3,(H,16,17)/t10-,13+/m0/s1
InChi Key
PTOIAAWZLUQTIO-GXFFZTMASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $37

    Add

    10 mg

    $70

    Add

    25 mg

    $92

    Add

    50 mg

    $163

    Add
    Product Description

    Tasimelteon is a melatonin (MT) receptor agonist.1 It selectively binds MT1 and MT2 receptors (Kis = 0.304 and 0.069 nM, respectively, in NIH3T3 cells expressing the recombinant human receptors) over a panel of 160 additional receptors and enzymes at 10 µM. Tasimelteon inhibits forskolin-induced cAMP accumulation with EC50 values of 0.79 and 1 nM in NIH3T3 cells expressing the MT1 or MT2 receptor, respectively. Formulations containing tasimelteon have been used in the treatment of non-24-hour sleep-wake disorder.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lavedan, C., Forsberg, M., and Gentile, A.J. Tasimelteon: A selective and unique receptor binding profile. Neuropharmacology 91, 142-147 (2015).