An anticholinergic agent
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Product Categories

Product Type

Biochemicals

Research Area

Immunology & Inflammation
Gastric Disease

Propantheline (bromide)

Item No. 23609

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl]-2-propanaminium, monobromide
CAS Number
50-34-0
Synonyms
  • SC-3171
Molecular Formula
C23H30NO3• Br
Formula Weight
448.4
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
O=C(OCC[N+](C(C)C)(C)C(C)C)C1C2=C(C=CC=C2)OC3=CC=CC=C31.[Br-]
InChi Code
InChI=1S/C23H30NO3.BrH/c1-16(2)24(5,17(3)4)14-15-26-23(25)22-18-10-6-8-12-20(18)27-21-13-9-7-11-19(21)22;/h6-13,16-17,22H,14-15H2,1-5H3;1H/q+1;/p-1
InChi Key
XLBIBBZXLMYSFF-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 mg

    $29

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    1 g

    $48

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    Product Description

    Propantheline is an anticholinergic agent.1,2,3 It inhibits contraction of isolated guinea pig ileum induced by acetylcholine (Item No. 23829) and reduces intensity of vagal-stimulated gastric contractions in rats.1 Propantheline (5 mg/kg, s.c.) increases gastric pH and prevents pyloric ligature-induced gastric ulcer formation in Shay rats.2 It also inhibits basal and pentagastrin-, but not histamine-, stimulated gastric secretion in a rhesus monkey model of chronic gastric fistula.3 Formulations containing propantheline have been used to treat stomach and intestinal spasms associated with irritable bowel syndrome.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

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