An organophosphate insecticide
Related Products
Labeled Version(s)
34517Dichlorvos-d6
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Dichlorvos

Item No. 23727

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
phosphoric acid, 2,2-dichloroethenyl dimethyl ester
CAS Number
62-73-7
Synonyms
  • DDVP
  • Dichlorovinyl Dimethyl Phosphate
  • NSC 6738
Molecular Formula
C4H7Cl2O4P
Formula Weight
221.0
Purity
≥98%
Formulation
A neat oil
Solubility(Learn about Variance in Solubility)
Chloroform: SolubleEthyl Acetate: SolubleMethanol: SolubleWater: Soluble
SMILES
Cl/C(Cl)=C/OP(OC)(OC)=O
InChi Code
InChI=1S/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3
InChi Key
OEBRKCOSUFCWJD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    100 mg

    $36

    Add
    Cayman Chemical
    Visit Our Environmental Toxicology Resource Center

    Explore additional resources to study natural toxins, pollutants including PFAS and 6-PPD-Q, and their biological effects.

    ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICES
    Product Description

    Dichlorvos is an organophosphate insecticide and inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE; IC50s = 269 and 44 nM, respectively).1 It also binds to the M2 muscarinic receptor in rat heart homogenates.2 Dichlorvos is lethal to 4-week old German cockroach (B. germanica) nymphs (LD50 = 0.108 μg per insect) and silkworms (B. mori) in third instar (LC50 = 6.63 mg/L) after 24 hours.3,4 It is lethal to zebrafish (D. rerio) embryos (LC50 = 39.75 mg/L after 24 hours) and decreases swimming activity of larvae 6 days after fertilization when administered at a concentration of 25 mg/L in tank water.5 Dichlorvos (150 ppm for 80 weeks) also increases the incidence of benign and malignant neoplasms in male rats from 47 to 88% as compared to controls.6 Formulations containing dichlorvos have been used as insecticides and miticides in agriculture, as well as in aquatic, commercial, industrial, and residential areas.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Petroianu, G.A., Schmitt, A., Arafat, K., et al. Weak inhibitors protect cholinesterases from stronger inhibitors (dichlorvos): In vitro effect of tiapride. Int. J. Toxicol. 24(2), 79-86 (2005).

    2. Silveira, C.L., Eldefrawi, A.T., and Eldefrawi, M.E. Putative M2 muscarinic receptors of rat heart have high affinity for organophosphorus anticholinesterases. Toxicol. Appl. Pharmacol. 103(3), 474-481 (1990).

    3. Qian, K., Wei, X., Zeng, X., et al. Stage-dependent tolerance of the German cockroach, Blattella germanica for dichlorvos and propoxu. J. Insect Sci. 10(1), 201 (2010).

    4. Zhang, Z.-Y., Wang, D.-L., Chi, Z.-J., et al. Acute toxicity of organophosphorus and pyrethroid insecticides to Bombyx mori. J. Econ. Entomol. 101(2), 360-364 (2008).

    5. Sişman, T. Dichlorvos-induced developmental toxicity in zebrafish. Toxicol. Ind. Health 26(9), 567-573 (2010).

    6. Reuber, M.D. Carcinogenicity of dichlorvos. Clin. Toxicol. 18(1), 47-84 (1981).