A synthetic peptide analog of ACTH 1-24
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Cosyntropin (acetate)

Item No. 23912

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
α1-24-corticotropin, acetate
CAS Number
60189-34-6
Synonyms
  • ACTH (1-24)
  • Adrenocorticotropic Hormone 1-24
  • Tetracosactide
Molecular Formula
C136H210N40O31S • XC2H4O2
Formula Weight
2993.5
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
[H]N[C@@H](CO)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N1CCC[C@H]1C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N2CCC[C@H]2C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@H](C(N3CCC[C@H]3C(O)=O)=O)CC4=CC=C(O)C=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC5=CNC6=C5C=CC=C6)=O)=O)CC7=CC=CC=C7)=O)CC8=CN=CN8)=O)=O)CCSC)=O)=O)CC9=CC=C(O)C=C9)=O.CC(O)=O
InChi Code
InChI=1S/C136H210N40O31S.C2H4O2/c1-75(2)109(127(200)154-71-106(181)156-88(31-13-17-52-137)114(187)158-89(32-14-18-53-138)115(188)159-91(35-21-56-149-134(142)143)116(189)164-96(37-23-58-151-136(146)147)131(204)175-60-25-39-104(175)126(199)173-111(77(5)6)128(201)163-90(33-15-19-54-139)120(193)171-110(76(3)4)129(202)169-101(65-80-43-47-84(180)48-44-80)132(205)176-61-26-40-105(176)133(206)207)172-125(198)103-38-24-59-174(103)130(203)95(34-16-20-55-140)157-107(182)70-153-113(186)99(66-81-68-152-87-30
InChi Key
XDSGCNRPXJYVQS-GLMYKROOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $85

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    1 mg

    $143

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    5 mg

    $623

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    10 mg

    $995

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    Product Description

    Cosyntropin is a synthetic form of adrenocorticotropic hormone (ACTH) residues 1-24.1 It increases the plasma concentration of hydrocortisone (Item No. 20739) in mares more rapidly and consistently than natural ACTH 1-24. Formulations containing cosyntropin have been used to diagnose adrenal deficiencies in humans, dogs, and horses.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Elier, H., Goble, D., and Oliver, J. Adrenal gland function in the horse: Effects of cosyntropin (synthetic) and corticotropin (natural) stimulation. Am. J. Vet. Res. 40(5), 724-726 (1979).