A vasoconstrictor
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Metaraminol (tartrate)

Item No. 23938

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
αR-[(1S)-1-aminoethyl]-3-hydroxy-benzenemethanol, 2R,3R-dihydroxybutanedioate
CAS Number
33402-03-8
Molecular Formula
C9H13NO2 • C4H6O6
Formula Weight
317.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 20 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
OC1=CC=CC([C@@H](O)[C@@H](N)C)=C1.OC([C@H](O)[C@@H](O)C(O)=O)=O
InChi Code
InChI=1S/C9H13NO2.C4H6O6/c1-6(10)9(12)7-3-2-4-8(11)5-7;5-1(3(7)8)2(6)4(9)10/h2-6,9,11-12H,10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t6-,9-;1-,2-/m01/s1
InChi Key
VENXSELNXQXCNT-IJYXXVHRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    50 mg

    $49

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    100 mg

    $93

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    Product Description

    Metaraminol is a vasoconstrictor.1,2 In vivo, metaraminol (0.05 mg/kg) increases cardiac output, mean arterial pressure, and coronary blood flow and decreases pulse rate in a canine model of cardiogenic shock.1 It increases survival in a canine model of hemorrhagic hypotension.2 Metaraminol also reverses acetoxycycloheximide-induced transient amnesia in a shock avoidance test in rats.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sarnoff, S.J., Case, R.B., Berglund, E., et al. Ventricular function. V. The circulatory effects of aramine; mechanism of action of vasopressor drugs in cardiogenic shock. Circulation 10(1), 84-93 (1954).

    2. Sarnoff, S.J., and Kaufman, H.E. Effect of aramine on the survival of dogs subjected to hemorrhagic hypotension. Circ. Res. 2(5), 420-423 (1954).

    3. Serota, R.G., Roberts, R.B., and Flexner, L.B. Acetoxycycloheximide-induced transient amnesia: Protective effects of adrenergic stimulants. Proc. Natl. Acad. Sci. USA 69(2), 340-342 (1972).